About 9 results found for searched term "ERK1/2 inhibitor 5" (0.182 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M49703 | ERK1/2 inhibitor 5 | ERK |
| ERK1/2 inhibitor 5 is a potent inhibitor of ERK1/2. | ||
| M5345 | Ulixertinib (BVD-523) | ERK |
| VRT752271; BVD523, Ulixertinib | ||
| VRT752271 (BVD-523, Ulixertinib) is an orally available, highly selective, ATP-competitive, reversible ERK1/2 inhibitor with an IC50 of <0.3 nM for ERK2 inhibition. | ||
| M9803 | MK-8353 | ERK |
| SCH900353 | ||
| MK-8353 (SCH900353) is an orally bioavailable, selective, and potent ERK1/2 inhibitor, with IC50 values of 23.0 nM and 8.8 nM, respectively. | ||
| M11529 | Temuterkib | ERK |
| LY3214996 | ||
| Temuterkib (LY3214996) is a selective, novel erK1/2 inhibitor with an IC50 of 5 nM against ERK1 and ERK2. It can effectively inhibit intracellular P-RSK1 in cancer cell lines with BRAF and RAS mutations. Temuterkib has strong antitumor activity in cancer models with altered MAPK pathways. | ||
| M14152 | ERK1/2 inhibitor 1 | ERK |
| ERK1/2 inhibitor 1 is a potent, orally bioavailable ERK1/2 inhibitor, showing 60% inhibition at 1 nM and an IC50 of 3.0 nM against ERK1 and ERK2, respectively. | ||
| M49692 | ERK1/2 inhibitor 7 | ERK |
| ERK1/2 inhibitor 7 is a potent ERK inhibitor with an IC50 of 0.94 nM for ERK2. | ||
| M49702 | ERK1/2 inhibitor 4 | ERK |
| ERK1/2 inhibitor 5 is a potent inhibitor of ERK1/2. | ||
| M49705 | ERK1/2 inhibitor 8 | ERK |
| ERK1/2 inhibitor 8 is a potent ERK inhibitor with an IC50 of 0.48 nM for ERK2. | ||
| M49720 | STE-MEK1(13) | ERK |
| STE-MEK1(13) (Ste-MPKKKPTPIQLNP-NH?) is a cell permeable ERK1/2 inhibitor (IC50: 13-30?μM). | ||
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